IPP5 inhibits neurite growth in primary sensory neurons by maintaining TGF-b/Smad signaling
نویسندگان
چکیده
Qing-Jian Han, Nan-Nan Gao, Guo-Qiang Ma, Zhen-Ning Zhang, Wen-Hui Yu, Jing Pan, Qiong Wang, Xu Zhang and Lan Bao* State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
منابع مشابه
IPP5 inhibits neurite growth in primary sensory neurons by maintaining TGF-β/Smad signaling.
During nerve regeneration, neurite growth is regulated by both intrinsic molecules and extracellular factors. Here, we found that inhibitor 5 of protein phosphatase 1 (IPP5), a newly identified inhibitory subunit of protein phosphatase 1 (PP1), inhibited neurite growth in primary sensory neurons as an intrinsic regulator. IPP5 was highly expressed in the primary sensory neurons of rat dorsal ro...
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